Paul Lin

Gelhorn HL, Tong S, McQuarrie K, Vernon C, Hanlon J, Maclaine G, Lenderking W, Ye X, Speck RM, Lackman RD, Bukata SV, Healey JH, Keedy VL, Anthony SP, Wagner AJ, Von Hoff DD, Singh AS, Becerra CR, Hsu HH, Lin PS, Tap WD. Patient-Reported Symptoms of Tenosynovial Giant Cell Tumors. Clin Ther. 2016 Mar 31. pii: S0149-2918(16)30145-X. doi: 10.1016/j.clinthera.2016.03.008. [Epub ahead of print]

Zhang C, Spevak W, Zhang Y, Burton EA, Ma Y, Habets G, Zhang J, Ewing T, Matusow B, Tsang G, Marimuthu A, Cho H, Lin J, Wu G, Wang W, Fong D, Nguyen H, Shi S, Womack P, Nespi M, Shellooe R, Carias H, Powell B, Light E, Sanftner L, Walters J, Tsai J, West BL, Visor G, Lin P, Nolop K, Ibrahim PN, Hirth P, Bollag G. RAF inhibitors that evade paradoxical MAPK pathway activation. Nature. 2015 Oct 22;526(7574):583-6. doi: 10.1038/nature14982. Epub 2015 Oct 14.

Thompson ML, Jimenez-Andrade JM, Chartier S, Tsai J, Burton EA, Habets G, Lin PS, West BL, Mantyh PW. Targeting cells of the myeloid lineage attenuates pain and disease progression in a prostate model of bone cancer. Pain. 2015 Sep;156(9):1692-702. doi: 10.1097/j.pain.0000000000000228.

William D. Tap, M.D., Zev A. Wainberg, M.D., Stephen P. Anthony, D.O., Prabha N. Ibrahim, Ph.D., Chao Zhang, Ph.D., John H. Healey, M.D., Bartosz Chmielowski, M.D., Ph.D., Arthur P. Staddon, M.D., Allen Lee Cohn, M.D., Geoffrey I. Shapiro, M.D., Ph.D., Vicki L. Keedy, M.D., Arun S. Singh, M.D., Igor Puzanov, M.D., Eunice L. Kwak, M.D., Ph.D., Andrew J. Wagner, M.D., Ph.D., Daniel D. Von Hoff, M.D., Glen J. Weiss, M.D., Ramesh K. Ramanathan, M.D., Jiazhong Zhang, Ph.D., Gaston Habets, Ph.D.… Show more

William D. Tap, M.D., Zev A. Wainberg, M.D., Stephen P. Anthony, D.O., Prabha N. Ibrahim, Ph.D., Chao Zhang, Ph.D., John H. Healey, M.D., Bartosz Chmielowski, M.D., Ph.D., Arthur P. Staddon, M.D., Allen Lee Cohn, M.D., Geoffrey I. Shapiro, M.D., Ph.D., Vicki L. Keedy, M.D., Arun S. Singh, M.D., Igor Puzanov, M.D., Eunice L. Kwak, M.D., Ph.D., Andrew J. Wagner, M.D., Ph.D., Daniel D. Von Hoff, M.D., Glen J. Weiss, M.D., Ramesh K. Ramanathan, M.D., Jiazhong Zhang, Ph.D., Gaston Habets, Ph.D., Ying Zhang, Ph.D., Elizabeth A. Burton, Ph.D., Gary Visor, Ph.D., Laura Sanftner, Ph.D., Paul Severson, Ph.D., Hoa Nguyen, Marie J. Kim, M.S., Adhirai Marimuthu, Ph.D., Garson Tsang, B.A., Rafe Shellooe, B.S., Carolyn Gee, M.Ed., Brian L. West, Ph.D., Peter Hirth, Ph.D., Keith Nolop, M.D., Matt van de Rijn, M.D., Henry H. Hsu, M.D., Charles Peterfy, M.D., Paul S. Lin, M.D., Sandra Tong-Starksen, M.D., and Gideon Bollag, Ph.D.
N Engl J Med 2015; 373:428-437July 30, 2015DOI: 10.1056/NEJMoa1411366 Show less

Puzanov P, Amaravadi RK, McArthur GA, Flaherty KT, Chapman PB, Sosman HA, Ribas A, Shackleton M, Hwu P, Chmielowski B, Nolop KB, Lin PS, Kim KB. Long-term outcome in BRAFV600E melanoma patients treated with vemurafenib: Patterns of disease progression and clinical management of limited progression. Eur J Cancer. 2015 Jul;51(11):1435-43. doi: 10.1016/j.ejca.2015.04.010. Epub 2015 May 13.

Gelhorn H, Tong S, Maclaine G, Healey J, Bukata S, Lackman R, Keedy V, Anthony SP, Wagner AJ, Von Hoff DD, Singh AS, Becerra CR, Hanlon J, Lenderking W, Murray L, Hsu H, Lin PS, Tap WD. Patient-Reported Outcome Instruments Meaningful and Relevant for Tenosynovial Giant Cell Tumor (TGCT): A Qualitative Study. American Society of Clinical Oncology 2015 Annual Meeting, Chicago, IL

Peterfy C, Tap WD, DiCarlo J, Wainberg ZA, Anthony SP , Zhang C, Staddon AP, Cohn AL, Shapiro GI, Puzanov I, Kwak EL, Hsu HH, Lin PS, Tong S, Healey JH. Oral CSF1-Receptor Inhibition with PLX3397 for Tenosynovial Giant Cell Tumor/Pigmented Villonodular Synovitis: MRI Assessment using Novel Modified RECIST, Tumor Volume Scoring, and Tissue Damage Scoring. European Musculo-Skeletal Oncology Society 2015 Annual Meeting, Athens, Greece.

Peterfy C, Tap WD, DiCarlo J, Wainberg ZA, Anthony SP , Zhang C, Staddon AP, Cohn AL, Shapiro G, Puzanov I, Kwak EL, Hsu HH, Lin PS, Tong S, Healey JH. MRI Assessment of Oral CSF1 Receptor Inhibition with PLX3397 for Tenosynovial Giant Cell Tumor Using Novel Modified RECIST, Tumor Volume Scoring and Tissue Damage Scoring Methods. Orthopaedic Research Society 2015 Annual Meeting, Las Vegas, NV.

Zhang C, Ibrahim, P, Zhang J, Burton EA, Habets G, Zhang Y, Powell B, West B, Wong B, Tsang G, Shellooe R, Carias H, Nguyen H, Marimuthu A, Zhang K, Oh A, Bremer R, Hurt C, Wu G, Nespi M, Spevak W, Lin P, Nolop K, Hirth P, Bollag G. Discovery and Pharmacology of a Highly Specific Dual FMS-KIT Kinase Inhibitor. Proceedings of the National Academy of Sciences. 2013 Apr 2;110(14):5689-94. doi: 10.1073/pnas.1219457110. Epub 2013 Mar 14. PMID: 23493555 [PubMed - indexed for MEDLINE]

Bollag G, Hirth P, Tsai J, Zhang J, Ibrahim PN, Cho H, Spevak W, Zhang C, Zhang Y, Habets G, Burton EA, Wong B, Tsang G, West BL, Powell B, Shellooe R, Marimuthu A, Nguyen H, Zhang KY, Artis DR, Schlessinger J, Su F, Higgins B, Iyer R, D'Andrea K, Koehler A, Stumm M, Lin PS, Lee RJ, Grippo J, Puzanov I, Kim KB, Ribas A, McArthur GA, Sosman JA, Chapman PB, Flaherty KT, Xu X, Nathanson KL, Nolop K. Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma. Nature… Show more

Bollag G, Hirth P, Tsai J, Zhang J, Ibrahim PN, Cho H, Spevak W, Zhang C, Zhang Y, Habets G, Burton EA, Wong B, Tsang G, West BL, Powell B, Shellooe R, Marimuthu A, Nguyen H, Zhang KY, Artis DR, Schlessinger J, Su F, Higgins B, Iyer R, D'Andrea K, Koehler A, Stumm M, Lin PS, Lee RJ, Grippo J, Puzanov I, Kim KB, Ribas A, McArthur GA, Sosman JA, Chapman PB, Flaherty KT, Xu X, Nathanson KL, Nolop K. Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma. Nature. 2010 Sep 30;467(7315):596-9. doi: 10.1038/nature09454. PMID: 20823850 [PubMed - indexed for MEDLINE] Show less