Tony Hoang

Tony Hoang

Atlanta, Georgia, United States
19K followers 500+ connections

About

I am an accomplished innovator and disruptor with 10+ years of artificial intelligence…

Activity

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Education

Licenses & Certifications

Volunteer Experience

  • Steering Committee Member

    RNA Institute

    • Primary responsibilities were to ensure the the development and growth of the RNA Institutes agenda by providing insight on issues concerning to operation, personnel, public relations, marketing, and external partners.

Publications

  • A ‘smart’ tube holder enables real-time sample monitoring in a standard lab centrifuge

    PLOS ONE

    The centrifuge is among the oldest and most widely used pieces of laboratory equipment, with significant applications that include clinical diagnostics and biomedical research. A major limitation of laboratory centrifuges is their “black box” nature, limiting sample observation to before and after centrifugation. Thus, optimized protocols require significant trial and error, while unoptimized protocols waste time by centrifuging longer than necessary or material due to incomplete sedimentation.…

    The centrifuge is among the oldest and most widely used pieces of laboratory equipment, with significant applications that include clinical diagnostics and biomedical research. A major limitation of laboratory centrifuges is their “black box” nature, limiting sample observation to before and after centrifugation. Thus, optimized protocols require significant trial and error, while unoptimized protocols waste time by centrifuging longer than necessary or material due to incomplete sedimentation. Here, we developed an instrumented centrifuge tube receptacle compatible with several commercial benchtop centrifuges that can provide real-time sample analysis during centrifugation. We demonstrated the system by monitoring cell separations during centrifugation for different spin speeds, concentrations, buffers, cell types, and temperatures. We show that the collected data are valuable for analytical purposes (e.g. quality control), or as feedback to the user or the instrument. For the latter, we verified an adaptation where complete sedimentation turned off the centrifuge and notified the user by a text message. Our system adds new functionality to existing laboratory centrifuges, saving users time and providing useful feedback. This add-on potentially enables new analytical applications for an instrument that has remained largely unchanged for decades.

    Other authors
    See publication
  • The Technology Development and Commercialization of 'Smart' Scientific Instrumentations

    PHD dissertation regarding the technology development and commercialization of smart scientific instruments such as a smart centrifuge test-tube holder and massively-parallel, single-molecule instrument using a commercial centrifuge bucket.

    See publication
  • A wireless centrifuge force microscope (CFM) enables multiplexed single-molecule experiments in a commercial centrifuge

    Review of Scientific Instruments

    The centrifuge force microscope (CFM) was recently introduced as a platform for massively parallel single-molecule manipulation and analysis. Here we developed a low-cost and self-contained CFM module that works directly within a commercial centrifuge, greatly improving accessibility and ease of use. Our instrument incorporates research grade video microscopy, a power source, a computer, and wireless transmission capability to simultaneously monitor many individually tethered microspheres. We…

    The centrifuge force microscope (CFM) was recently introduced as a platform for massively parallel single-molecule manipulation and analysis. Here we developed a low-cost and self-contained CFM module that works directly within a commercial centrifuge, greatly improving accessibility and ease of use. Our instrument incorporates research grade video microscopy, a power source, a computer, and wireless transmission capability to simultaneously monitor many individually tethered microspheres. We validated the instrument by performing single-molecule force shearing of short DNA duplexes. For a 7 bp duplex, we observed over 1000 dissociation events due to force dependent shearing from 2 pN to 12 pN with dissociation times in the range of 10-100 s. We extended the measurement to a 10 bp duplex, applying a 12 pN force clamp and directly observing single-molecule dissociation over an 85 min experiment. Our new CFM module facilitates simple and inexpensive experiments that dramatically improve access to single-molecule analysis.

    Other authors
    See publication

Patents

  • ADAPTERS AND INSTRUMENT MODULES FOR USE IN A CENTRIFUGE BUCKET

    Filed US 15/356,041

    An adapter is connectable to any one of a plurality of different instrument modules so that the connected adapter and any one of the plurality of different instrument modules is positionable within a centrifuge bucket. The adapter includes, for example, a support positionable in a first portion of the centrifuge bucket so that the any one of the plurality of different instrument modules is positionable in a second portion of the centrifuge bucket, a processor attachable to the support, a power…

    An adapter is connectable to any one of a plurality of different instrument modules so that the connected adapter and any one of the plurality of different instrument modules is positionable within a centrifuge bucket. The adapter includes, for example, a support positionable in a first portion of the centrifuge bucket so that the any one of the plurality of different instrument modules is positionable in a second portion of the centrifuge bucket, a processor attachable to the support, a power source or a connector to a power source operably electrically connected to the processor, an interface operably connected to the processor for receiving data from the any one of the plurality of different instrument modules, and a transmitter for wirelessly transmitting data from the processor to a remote location.

    See patent
  • SEPARATION SAMPLING MODULES FOR USE WITHIN A BUCKET OF A CENTRIFUGE

    Filed US 15/356,023

    A separation sampling module for use within a bucket of a centrifuge for monitoring separation of a sample in a container includes a housing operable for supporting the container for containing the sample and removably positionable within the bucket of the centrifuge, at least one light source for illuminating the sample, at least one light detector for detecting light from the sample, an accelerometer for measuring acceleration of the housing, and at least one of a power source and a connector…

    A separation sampling module for use within a bucket of a centrifuge for monitoring separation of a sample in a container includes a housing operable for supporting the container for containing the sample and removably positionable within the bucket of the centrifuge, at least one light source for illuminating the sample, at least one light detector for detecting light from the sample, an accelerometer for measuring acceleration of the housing, and at least one of a power source and a connector operably connectable to a power source for use in powering the at least one light source. Light from the at least one light source passing through the sample defines a light path disposed in a direction across the direction of a centrifugal force when the separation sampling module is disposed in the bucket and rotated in the centrifuge.

    See patent
  • ELECTRICAL SYSTEMS,AND SEPARATION SAMPLING MODULES FOR USE WITHIN A BUCKET OF A CENTRIFUGE

    Filed US 14/927,026

    A separation sampling module for use within a bucket of a centrifuge for monitoring separation of a sample in a container includes a housing operable for supporting the container for containing the sample and removably positionable within the bucket of the centrifuge, at least one light source for illuminating the sample, at least one light detector for detecting light from the sample, and at least one of a power source and a connector operably connectable to a power source for use in powering…

    A separation sampling module for use within a bucket of a centrifuge for monitoring separation of a sample in a container includes a housing operable for supporting the container for containing the sample and removably positionable within the bucket of the centrifuge, at least one light source for illuminating the sample, at least one light detector for detecting light from the sample, and at least one of a power source and a connector operably connectable to a power source for use in powering the at least one light source. Light from the at least one light source passing through the sample defines a light path disposed in a direction across the direction of a centrifugal force when the separation sampling module is disposed in the bucket and rotated in the centrifuge.

    See patent
  • CENTRIFUGE FORCE MICROSCOPE MODULES AND SYSTEMS FOR USE IN A BUCKET OF A CENTRIFUGE

    Filed US 14/530,434

    A centrifuge force microscope module for use within a bucket of a centrifuge in measuring a characteristic of a sample under a centrifugal force and/or in monitoring a sample under a centrifugal force. The centrifuge force microscope module includes an electronics module and an optical module. The electronics module includes a housing removably disposable in the bucket of the centrifuge, and at least one of a power source and a connector operably connectable to a power source for powering the…

    A centrifuge force microscope module for use within a bucket of a centrifuge in measuring a characteristic of a sample under a centrifugal force and/or in monitoring a sample under a centrifugal force. The centrifuge force microscope module includes an electronics module and an optical module. The electronics module includes a housing removably disposable in the bucket of the centrifuge, and at least one of a power source and a connector operably connectable to a power source for powering the electronics module. The optical module is operable to receive and direct light from the sample. The optical module is releaseably connectable to the housing of the electronics module.

    See patent
  • ELECTROPHORESIS CONTROLLERS, SENSORS, AND METHODS FOR CONTROLLING ELECTROPHORESIS PROCESSES

    Filed US 14/520,624

    An electrophoresis controller for use with an electrophoresis apparatus having a gel matrix disposed between electrodes for separation of particles along with a tracking dye. The electrophoresis controller includes a sensor system and a controller. The sensor system includes a support, a light emitter, and a light receiver. The support includes a first portion positionable on a first side of the gel matrix and a second portion positionable adjacent a second side of the gel matrix. The light…

    An electrophoresis controller for use with an electrophoresis apparatus having a gel matrix disposed between electrodes for separation of particles along with a tracking dye. The electrophoresis controller includes a sensor system and a controller. The sensor system includes a support, a light emitter, and a light receiver. The support includes a first portion positionable on a first side of the gel matrix and a second portion positionable adjacent a second side of the gel matrix. The light emitter is positioned on the first portion of the support for emitting light onto one side of the gel matrix. The light receiver is positioned on the second portion of the support adjacent to the other side of the gel matrix for receiving light from the light source as it is passing through the gel matrix. At least one of the light emitter and the light receiver includes a light guide having a first end and a second end. The first end is positioned on the support and facing the gel matrix, and the second end is remote from the sensor system. The controller is operably connected to the sensor for monitoring a change in the light from the illuminated gel matrix due to migration of the tracking dye into the illuminated gel matrix and received by the light receiver.

    See patent

Honors & Awards

  • "Radical Candor" Award

    AudioEye

  • Atlanta Startup Runway First Place Winner

    Atlanta Startup Runway

    The mission of Startup Runway is introducing top under-represented founders to professional investors. Finalists are chosen from hundreds of applicants. $10k award.

  • Albany Business Review's 40 Under 40 2017

    Albany Business Review

    Albany Business Review's 40 Under 40 honorees were selected from about 400 nominations. They represent the incredible young talent from many of the Capital Region’s important industries including finance, health care, technology and hospitality.

  • Finalist

    New York State Business Competition

    Finalist at the New York State Business Competition

  • Tech Awards: Technology Entrepreneur

    Albany Business Review

    Tony Hoang, a Ph.D. students at the University at Albany, has six patents for technologies that will be sold through his company Advanced Modular Instruments. He is the winner of this year's Technology Entrepreneur Award.

  • Chemistry Student Breaks University Patent-Pending Record

    University at Albany

    Tony Hoang, a Ph.D. chemistry candidate, will launch his biotech startup this month with six pending utility patents.

    That number breaks the University at Albany student record.

  • Forbes 30 Under 30 Candidate

    Forbes Under 30

    Hoang, a Ph.D. chemistry candidate and member of the RNA Institute, has been selected to pitch his scientific accessory company - Advanced Modular Instruments (AMI) - during the annual Forbes 30 Under 30 summit.

  • Blackstone LaunchPad Business Competition 1st Place Winner

    Blackstone LaunchPad

    In April, the Ph.D. chemistry candidate won University at Albany’s first Blackstone LaunchPad business competition, presenting his idea for a scientific accessory company called Advanced Modular Instruments (AMI).

  • Finalist at The Patashnick Entrepreneurial Challenge

    Patashnick Entrepreneurial Challenge

    The Patashnick Entrepreneurial Challenge offers stipend support for select UAlbany students who are pursuing dreams of innovative startup companies.

Languages

  • English

    Native or bilingual proficiency

  • Vietnamese

    Native or bilingual proficiency

Organizations

  • Biophysical Society

    Member

    - Present
  • American Chemical Society

    Member

    - Present

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